A person has an addiction when he or she becomes dependent on or craves a drug all of the time.

In Europe, Spain seized the most cocaine including seizures which took place in international waters. Recent measures by the Netherlands at the international airport in Amsterdam and in the Netherlands Antilles have reduced the number of cocaine couriers utilising the route from Curacao to the Netherlands. Nevertheless, Dutch authorities seized the second highest amount of cocaine among European nations, followed by Italy, France and Germany.

Juvenile and Family Drug Courts: The overall success of adult drug court programs has encouraged development of other programs such as juvenile drug courts and family courts. Juvenile and family drug courts began in 1995. Since then, approximately 12,500 juveniles have enrolled in juvenile drug courts, with 82 percent of participants being male. Adolescents involved in juvenile drug court programs have extensive histories of drug use, often beginning between the ages of 10 and 14. Drugs of choice include crack cocaine, heroin, methampethamines, and poisonous inhalants. Working with juveniles requires different strategies from those used in adult drug courts. For example, juvenile drug courts focus on the family of the drug offender. They work more closely with community agencies to keep the young offender off drugs. Also, juvenile drug courts offer closer judicial supervision of young offenders than the supervision typically available by traditional courts. The goals of juvenile drug courts include helping adolescents become drug-free, reducing rates of repeat criminal activity, improving school performance, and helping the young offender form a productive and healthy relationship with members of his or her community.

The severity of alcohol-induced impairment depends on the amount of alcohol present in the bloodstream, which is based on a person's blood alcohol content (BAC) percentage. Most people begin to feel the effects of alcohol when their BAC ranges between 0.03% and 0.059%. At this point, the person feels mild euphoria, relaxation, and talkativeness, but he or she suffers from impaired alertness, judgment, coordination, and concentration.

Khat has been encountered by law enforcement in highway interdictions in Missouri.

Current reports show that diversion of hydrocodone products such as Vicodin®, and oxycodone products such as OxyContin® continues to be a problem in Missouri.

LSD is found in Missouri, though its abuse is not believed to be widespread.

Cocaine and crack cocaine are easily available in both the St. Louis and Kansas City areas of Missouri and are abused by all social and ethnic groups.

Marijuana is continuing problem throughout the state of Missouri.

The availability of PCP is more of a problem in the Kansas City area of Missouri, but St. Louis law enforcement reports a spike in the availability of the drug in the St. Louis area on from time to time.