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Facts About Vicodin You Should Be Aware Of
Any individual that wants to know facts about Vicodin, must know that these facts are actually closely linked to its active ingredient. The effectiveness of Vicodin as a painkiller is completely based on hydrocodone - also pharmaceutically and chemically known as dihydrocodeinone.
This drug is a semi-synthetic opioid that results from either one of two naturally found opiates: codeine and thebaine. Vicodin is a potent narcotic analgesic; in general terms, the drug is only orally active. Hydrocodone is readily available in tablets, syrups and capsules.
Hydrocodone is usually compounded with other non-opioid substances that include paracetamol (especially in the case of Vicodin), also commonly referred to as acetaminophen, or ibuprofen (in the case of Vicoprofen) to supply a feasible synergy of painkilling effects between hydrocodone and the non-opioid substances present.
The specific niche where hydrocodone is most frequently employed is really as an intermediate painkiller that acts centrally. Sudden interruption of Vicodin may possibly lead to withdrawal signs and symptoms.
Due to concerns and issues in regards to hepatic damage from interrupted use of paracetamol at high doses, a number of pharmaceutical companies are creating extended-release capsules along with other types of hydrocodone alone.
The Makers of Vicodin
Initially developed by Knoll, a German pharmaceutical company, hydrocodone is produced by virtually linking a hydrogen component to a specific number of molecules present in the formula of codeine. When the substance was initially released, the company thought that this approach would, in fact, make the codeine much easier to tolerate by the liver and stomach. Therefore it was intended to make it less dangerous to the patient.
In the course of this time, the government of the USA and the medical officials of the nation were facing a continuously growing issue. It was a known fact that a large number of individuals were already showing signs of addiction to the Opium-derived substances present in the most well-known cough tablets and syrups of the time.
The government of the United States funded research to analyze hydrocodone along with other medication compounds as alternative, less-addictive analgesics.
World-famous scientists and chemists were called in to lead the research. They studied and analyzed the primary effects, as well as the safety along with the potential side effects of a huge selection of distinct drugs. These drugs included morphine and the most potent type of codeine, but also the newly discovered hydrocodone - present in Vicodin.
Scientists discovered that hydrocodone was actually one of the most powerful substances with regards to analgesic effectiveness along with the possibility to predict a number of its unwanted effects. On the other hand, there was an issue with hyrocodone - it produced a significant euphoric effect on the animals that were studied.
The active ingredient in Vicodin is potent, but in addition, it holds the possibility to become extremely addictive. Pharmacologists stated that it could be highly possible for a person to develop addiction to Vicodin - the patient would not even know that he or she is developing an addiction to the drug.
In spite of these discoveries, hydrocodone soon became a tremendous success on the pharmaceutical market of the US and in the following years Vicodin continued to grow a solid reputation as a painkiller, in spite of its increased potential to develop addiction.
Other facts about Vicodin or, more specifically, Hydrocodone include the early FDA approval: the substance was legally authorized in the 1940s. Hydrocodone is marketed in different forms - the most notorious trade name remains Vicodin. Hycodan was the initial trade name.
Vicodin is a narcotic that relieves and eventually kills pain by binding to opioid receptors inside the brain and spine. It can be used with or without food or water - depending on the user's desire. However, when Vicodin is ingested with alcohol, it actually intensifies the feeling of drowsiness. The active ingredient in Vicodin can also display chemical interactions with a number of oxidase inhibitors, as well as other substances that lead to drowsiness.
Vicodin is, in fact, listed in the pregnancy category C of the FDA. Animal reproduction research and studies have demonstrated that Vicodin has a severe impact on the fetus.
On the other hand, there are actually no adequate scientific studies on people, but potential positive aspects may well warrant use of the substance in pregnant women in spite of possible hazards. On top of that, an infant of a mother using the drug may possibly show breathing difficulties or withdrawal signs and symptoms.
Vicodin is a prescription drug and, as a consequence, it should only be used under strict medical supervision - otherwise addiction is likely to step in and severely affect the patient.
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